Grad student Eric Cord's roommate and best friend Ted gives Eric a gun with silver bullets and confesses that he is a werewolf, bitten while he was working on a boat owned by Captain Janos Skorzeney. A pentagram appears on his palm a few hours before he changes. The only way to end the curse is to kill the original werewolf in this bloodline. Eric ties Ted up but he changes, breaks free and bites Eric, who is forced to shoot him. Charged with murder, Eric jumps bail and begins searching for the werewolf who bit Ted, who turns out to be Skorzeney. Eric is pursued by "Alamo Joe" Rogan, a bounty hunter who saw Eric change and now uses silver bullets.